From observable evidence to a registered forecast
We compile public evidence revisions, distinguish substantive changes from routine edits, and identify claims for review. That history supports your evidence packages and briefings. We also register forecasts for defined guideline, label, and coverage actions. Whether claim history improves those forecasts is under test; current forecasts use the decision's own review record (how the number is formed).
Turn a broad question into a verifiable forecast
Before any evidence is read, the question you bring is rewritten into four parts: a named authority, a defined action, a target population, and a deadline. In that form, the institution either takes the action by the date or it does not.
- 1 · Authority Who decides
- NCCN NSCLC Guidelines Panel
- 2 · Action Specified action
- A first-line listing, at any NCCN category
- 3 · Population Patient population
- EGFR exon 20 insertion mutation-positive metastatic non-squamous NSCLC
- 4 · Deadline Date it must happen by
- 2027-07-31
That is the first record: NCCN lists sunvozertinib as a first-line option in EGFR exon 20 insertion NSCLC, which resolves by reading the guideline's own tables. What is still under test is on the research page.
Extract, classify, prioritize, register
Classification distinguishes new evidence and changed recommendations from routine document edits. Where sources disagree, the record shows that disagreement before summarizing the claim.
Extract
We rebuild the claim's history across label revisions, guideline editions, and published trials. We date each wording change and citation and link it to its source.
Classify
We distinguish new trial results supporting a claim, changes to published recommendations, and routine edits such as citation cleanup. We record which qualifier changed and what evidence supports the change.
Prioritize
We rank claims for commercial review using documented changes: a qualifier removed, an evidence gap identified, or a new restriction in a coverage policy.
Register
The probability that the named authority (such as NCCN, FDA, or CMS) takes a defined action by the deadline is registered before the outcome is known.