Use Cases

Use it when the data might have moved since the last look.

Send one claim and one context for a fit check. We'll tell you whether a dossier makes sense — free, no commitment.

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Diligence Contexts

You are in the right place if your team is asking one of these questions.

Each context maps to a specific diligence workflow. The common thread: a claim is in motion, and your team needs a structured read before the next decision.

Pre-ADCOM and Advisory Committee

Track how the evidence around a drug is shifting in the months before an FDA advisory committee meeting.

Example questions

What is hardening: Which clinical claims have the strongest supporting evidence going into the ADCOM?

What is weakening: Which claims have lost citations, been reverted, or had their evidence base narrow?

What remains contested: Which safety or efficacy points are still under active editorial dispute?

Useful terms

ADCOMhardeningweakeningcontestedevidence movementsource trailcaveats

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Catalyst and Data Readout

Assess whether a clinical readout supports or undermines the key claims in a company thesis.

Example questions

Load-bearing claims: Which claims in the asset story would break the thesis if challenged?

Evidence fit: Does the new data strengthen, weaken, or leave unchanged the core clinical narrative?

Competitor implications: How does the readout affect competing claims in the same therapeutic area?

Useful terms

readoutthesis testingload-bearing claimevidence shiftdiligence read

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Competitive Tracking

Monitor how claims about competing assets are evolving across the public record.

Example questions

Claim divergence: Is a competitor's narrative hardening while yours is fragmenting or unresolved?

Citation landscape: Are competing drugs accumulating stronger citation support in the public record?

Editorial signals: Are there reverts, disputes, or citation replacements on key competitive claims?

Useful terms

competitivedivergencecitation trackingeditorial signalsreverts

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Safety Signal Monitoring

Track whether a safety concern is gaining editorial weight, new citations, or regulatory attention.

Example questions

Signal strengthening: Are safety concerns being cited more frequently, moved to the lead, or gaining editorial consensus?

Pre-formal action: What evidence movement is visible before a formal regulatory or labeling action?

Class effects: Is a safety signal spreading across related assets in the same class?

Useful terms

safety signaleditorial weightlead movementclass effectpre-formal

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Diligence and Thesis Review

Test whether a thesis rests on claims that are hardening, weakening, stalling, or reversing.

Example questions

Claim-state map: Which assumptions in the investment thesis are most vulnerable to evidence shift?

Caveat inventory: What caveats, limitations, or qualifications have been lost or softened over time?

Expert questions: What should diligence ask the management team or KOLs based on the public record?

Useful terms

thesisclaim mapcaveatsKOLdiligence questions

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Boundary

Every dossier has the same structure

One claim, one context, one timeline. What changed, what the data shows, what to watch. Always with explicit limits on what the read does and does not say.